Aptamer Ppt ppts

Searching:
Download
Aptamer Ppt - Fast Download

Download Aptamer Ppt from our fatest mirror

PowerPoint Presentation

6064 dl's @ 2330 KB/s

ppt
PowerPoint Presentation

Scott A. Barros, PhD, DABT Sr. Scientist, Toxicology What is an Aptamer? Aptamer Structure Medicinal Chemistry Process Increased plasma stability Increased affinity Increased potency Considerations in Safety Assessment of Aptamers In general, aptamers have toxicological properties similar to ...

http://www.massbio.org/writable/committees/presentations/mbc_21feb2008.ppt

Date added: October 30, 2011 - Views: 101

ppt
PowerPoint Presentation

... • Structural studies of aptamer-ligand complexes have provided a wealth of information regarding RNA structure and ligand interaction • Most aptamers exhibit conformational changes upon binding to ligand (induced fit binding) ...

http://chemistry.creighton.edu/~jksoukup/lecRiboswitches2008.ppt

Date added: October 31, 2011 - Views: 59

ppt
PowerPoint Presentation

Impact Aptamer recognition elements enable detection of nucleic acids, proteins, small molecules, inorganic ions Accomplishments Smart electrode surfaces allow real-time detection of small molecule analytes Device integration: ...

http://www.strategicstudiesinstitute.army.mil/pdffiles/strat20/panel-1-kokoska/kokoska.ppt

Date added: October 12, 2011 - Views: 53

ppt
Label-Free Protein Biosensor Based on Aptamer-Modified Carbon ...

Label-Free Protein Biosensor Based on Aptamer-Modified Carbon Nanotube Field-Effect Transistors Kenzo Maehashi, Taiji Katsura, Kagan Kerman, Yuzuru Takamura,

http://light.eecs.berkeley.edu/courses/ee235_sp07/student_presentations/0305/(4)%2003052007_Ryan_EE235.ppt

Date added: November 30, 2012 - Views: 14

ppt
PowerPoint Presentation

Can’t predict effects of aptamer location Must determine “optimal input-module location within intronic sequence space” for each regulatory device But is it really modular? “We selected the SMN1 minigene because key regulatory sequences are located in its exon regions, ...

http://openwetware.org/images/4/44/Tinaandrew20.385.ppt

Date added: May 6, 2013 - Views: 4

ppt
Folie 1 - imb-jena.de

The Aptamer Database is a comprehensive, annotated repository for information about aptamers and in vitro selection. This resource is provided to collect, organize and distribute all the known information regarding aptamer selection.

http://www.imb-jena.de/www_bioc/3D/3D_LECTURE_2005_2.ppt

Date added: June 11, 2013 - Views: 4

ppt
DNA-based cell targeting - OpenWetWare - Main Page - OpenWetWare

Part 1: Find and test aptamer that binds cell-surface protein Literature search Assay: use fluorescently labeled aptamer Part 2: Conjugate a protein to single stranded DNA. Part 3: Testing Fluorescently labeled DNA again!

http://openwetware.org/images/d/d2/Targeting.ppt

Date added: March 31, 2012 - Views: 9

ppt
NCI Alliance for Nanotechnology in Cancer: Research Advances ...

... ErbB3 Targeted Aptamer-Nanoparticle Conjugate, Massachusetts General Hospital, Boston, Mass. Carolina Center of Cancer Nanotechnology Excellence, University of North Carolina, Chapel Hill, N.C. Nanosystems Biology Cancer Center, ...

http://deainfo.nci.nih.gov/advisory/bsa/bsa0608/presentations/monday/1001%20Rosen.ppt

Date added: June 26, 2012 - Views: 29

ppt
The Detrimental Impact of Chronic Renal Insufficiency

Factor IXa Inhibition Aptamer Technology Overview and First Results with RB006/RB007 Mauricio G. Cohen, MD Associate Professor of Medicine Director, Cardiac Cath Lab

http://www.clinicaltrialresults.org/Slides/Factor%209%20inhibition%20via%20aptamer.ppt

Date added: November 8, 2011 - Views: 35

ppt
PowerPoint Presentation

He, et al., Chemical Science, 2011 Aptamer-Based SERS Assay L. He, et al., Chemical Science, 2011 Raman shift (cm-1) Assignments Aptamer (*) 1316 Adenine (ring stretching) 1022 DNA backbone(PO2- stretching) 792 thymine, cytosine 735 Adenine (ring breathing) ...

http://blog.lib.umn.edu/chaynes/8152/Lecture21_clh_class.ppt

Date added: November 25, 2011 - Views: 11

ppt
Slide 1

One anti-Rev aptamer: binds peptide in alpha-helical conformation Another anti-Rev aptamer: binds peptide in an extended conformation MS2 protein as beta sheet bound via protruding side chains DNA synthesizer T7 prom PCR site random 1015 T7 polymerase, ...

http://www.cs.duke.edu/~reif/temp/aptamers/evolving%20aptamers/overview%20slides%20of%20SELEX/aptamers04.ppt

Date added: May 5, 2013 - Views: 34

ppt
PowerPoint Presentation

Introduction Basic processes Features 2. Methods 3. Aptamer base 1. SELEX (systematic evolution of ligands by exponential enrichment) is a process that ...

http://www.biopharmagen.com/SELEX%20by%20%20褚畅.ppt

Date added: November 24, 2013 - Views: 32

ppt
Inquiry into Life Twelfth Edition - McGraw-Hill

... in response to ligand binding are called riboswitches Riboswitch Action Region that binds to the ligand is an aptamer An expression platform is another module in the riboswitch which can be: ...

http://highered.mcgraw-hill.com/sites/dl/free/0072995246/444682/chapt07_lecture.ppt

Date added: November 26, 2011 - Views: 26

ppt
PowerPoint Presentation

… an ‘expression platform’ for gene regulation. A metabolite-binding ‘aptamer’ domain and … Riboswitch Functions U U U U U X 3 4 2 1 Direct (protein-free) binding of metabolite to RNA Metabolite-dependent regulation of genes These two activities are accomplished by two functionally ...

http://ender.bu.edu/~tgardner/be209/lectures/15/15%20Slides.ppt

Date added: February 2, 2012 - Views: 15

ppt
PowerPoint Presentation

Aptamer antagonist of tissue factor pathway inhibitor. Improved thrombin generation in plasma from subjects with FVIII deficiency. Improved clot times as measured by thromboelastography in monkeys depleted of FVIII. Waters, Blood, 2009. Fucoidans.

http://www.ohsu.edu/xd/health/services/cancer/getting-treatment/why-ohsu/for-healthcare-professionals/continuing-ed/upload/Recht_12-01-21-bleeding-2012.pptx

Date added: April 19, 2013 - Views: 15

ppt
Overview of your immune system - Information Management ...

... 657 RNA aptamers -- antibody-like properties Vitamin b12-binding RNA aptamer Slide 10 Let the immune system make enzymes for you Wedemayer et al. (1997) Science 276, 1665-1669. Catalytic antibody that hydrolyzes cocaine Zhu et al., 2006, ...

http://www.its.caltech.edu/~bi1/archives/files_2011/lectures/lecture26/lecture26.ppt

Date added: January 29, 2013 - Views: 9

ppt
Indicator Displacement Assays for Solute Sensing

Indicator Displacement Assays for Solute Sensing Julee Byram Mecozzi Group May 10, 2007 * * * * * * * * * * * * * * * * * * * * * * * * * Aptamer-Based Sensor for Cocaine Stojanovic, M.N.; Prada, P.; Landry, D.W. J. Am. Chem. Soc. 2001, 123, 4928 518 nm 472 nm Kd ~ 100 μM Cocaine concentration ...

http://www.chem.wisc.edu/areas/organic/studsemin/byram/byram-sem.ppt

Date added: November 2, 2011 - Views: 14

ppt
Duke Clinical Research Institute - dukecardiologyfellows

VWF Aptamer and Murine Carotid Injury Nimjee S et al. Mol Therapy 2011 Universal Antidotes for VWF Aptamer CDP and VWF Aptamer PDA-DPA and VWF Aptamer Oney S et al. Nature Medicine Oct 4, 2009. Extracellular DNA Traps and Thrombosis Fuchs. PNAS 2010;107 ...

http://www.dukecardiologyfellows.org/dcfblog/wp-content/uploads/translational-science-20121.ppt

Date added: May 5, 2013 - Views: 7

ppt
PowerPoint Presentation

... Another RNA aptamer example: adenosine aptamer Class II ligase ribozyme Pitt & Ferré-D’Amaré, J. Am. Chem. Soc., 2009, 131 (10), pp 3532–3540 Class II ligase ribozyme Rapid Construction of Empirical RNA Fitness Landscapes Jason N. Pitt and Adrian R. Ferré-D’Amaré* Science 2010: ...

http://chem.ps.uci.edu/~aluptak/110715_UK_Lecture.ppt

Date added: May 3, 2013 - Views: 6

ppt
PowerPoint Presentation

CU Boulder Research, Scholarly Activity, and Creative Works GSAC April 30, 2010 Russ Moore, Interim VC Research Research & Scholarly Works Remarkable record of research and scholarly works achievement across all schools and colleges on our campus see http://www.colorado.edu/research/achievements ...

http://www.colorado.edu/graduateschool/aboutus/gsac/minutes/april10/GSAC(S10)RMpresentation.ppt

Date added: August 1, 2013 - Views: 196

ppt
Label-Free Protein Biosensor Based on Aptamer-Modified Carbon ...

Label-Free Protein Biosensor Based on Aptamer-Modified Carbon Nanotube Field-Effect Transistors Author: Ryan Yang Last modified by: Ryan Yang Created Date: 3/5/2007 4:19:31 PM Document presentation format: 如螢幕大小 Other titles:

http://light.eecs.berkeley.edu/courses/ee235_sp07/student_presentations/0321/%286%29%2003212007_Ryan_EE235.ppt

Date added: May 11, 2013 - Views: 8

ppt
Applications of Spectrophotometry - Schreiner University

This aptamer then behaves as a custom made, synthetic “antibody”. Sensors based on Luminescent Quenching Luminescence intensity is proportional to the concentration of the emitting species if concentrations are low enough.

http://faculty.schreiner.edu/bholloway/S%202006%20CHEM%203402%20Applications%20of%20Spectrophotometry-Sean%20Collins.ppt

Date added: April 23, 2012 - Views: 23

ppt
Extensive and global regulation of transcription Shifts in

The portion that directly binds the ligand is the aptamer. Expression can be affected transcriptionally or post-transcriptionally. The ribD operon controls synthesis and transport of riboflavin and FMN.

http://www.sbs.utexas.edu/herrin/bio344/lectures/L11_proktransc4_Organ1.ppt

Date added: April 12, 2012 - Views: 12

ppt
PowerPoint Presentation

... Selection against proteins - Selection of new ribozymes (RNA world) The ATP aptamer structure Nucleolin RNA Targets B1 10-50nM (5’ETS) Mouse B2 50-100nM (5’ETS) ...

http://www.mol.biol.ethz.ch/groups/allain_group/teaching/Ribozyme-course.ppt

Date added: October 7, 2011 - Views: 37

ppt
No Slide Title

Anti-terminator Aptamer Vitamin B1 biosynthesis in bacteria: TPP-mediated attentuation control: E. Nudler and coworkers: (Mironov et al., Cell, 2002) Thiamine pyrophosphate are the metabolites that alter conformation.

http://in.bgu.ac.il/fohs/Documents/Presentations/dbarash_riboswitch_presentation_2013.ppt

Date added: July 30, 2013 - Views: 5

ppt
PowerPoint Presentation

S-aptamer-tagged ARE and mtARE reporters were used for in vivo Crosslinking-coupled RNP purificaiton followed by RPA assay High-mobility group A2 (HMGA2) 3’ UTR contains seven sites for the endogenous Let-7 High-mobility group A2 (HMGA2) ...

http://www.microbio.uab.edu/ptrm/2008/ChaoLi/li92308.ppt

Date added: June 1, 2013 - Views: 4

ppt
PowerPoint Presentation

aptamer. fragments. Anal Method . ... Arsenics: 10 ppt (WHO acceptable limit: 10 ppb) Lead: 100 ppt (2 orders of magnitude below the EPA standard limit) 2-3 orders of magnitude. Small molecules. 7 nM (5 orders of magnitude more sensitive than the colorimetric method)

http://nanodiscoveryinc.com/yahoo_site_admin/assets/docs/NanoDLSay.50102502.pptx

Date added: June 10, 2013 - Views: 11

ppt
PowerPoint Presentation

REG1: Pegnivacogin + AnivamersenRegado Biosciences, Inc. Novel Anticoagulation System. RNA aptamer . Factor IXa inhibitor. Controlling agent. Active. Specific

http://clinicaltrialresults.org/Slides/RADAR%20ACC11%20LBCT%20040311%20final_Povsic.ppt

Date added: November 10, 2011 - Views: 11

ppt
PowerPoint Presentation

... First Anti Angiogenic Agent 28 Base RNA Aptamer NON-IMMUNOGENIC NATURE Selectively binds extra cellular VEGF 165 DOES NOT EFFECT NORMAL VASCUALR GROWTH BEVACIZUMAB (AVASTIN) Humanized mono-clonal antibody. Active Against all ...

http://www.jdosmp.org/pps/antiVEGF_rs.ppt

Date added: June 2, 2013 - Views: 24

ppt
PowerPoint Presentation

... Multiple Isoforms of VEGF-A Are Generated from Exon Splicing VEGF Inhibition in AMD FDA approved Pegaptanib Aptamer Specific for VEGF-A isoform 1651 Ranibizumab Recombinant, ...

http://www.projectsinknowledge.com/Init/MC/1772/1772-Slides.ppt

Date added: October 16, 2011 - Views: 72

ppt
Slide 1

Operation of riboswitch successfully modeled with Kinfold (Vienna RNA) Aptamer/Antiterminator/Terminator competition Evidence for natural selection of reliably folding sequences Probability of no selection P ~ 0.01 * * Title: Slide 1 Author:

http://www.math.rutgers.edu/events/smm/michael.widom.ppt

Date added: May 11, 2013 - Views: 8

ppt
PowerPoint Presentation

... Intracellular Lung Tarceva, Iressa Aptamer Cell Surface, Intracellular Renal, Lung AS1411 (in dev.) Peptide Cell Surface, Intracellular Breast, Thyroid RGD (in dev.) Targeting Agent Mode of Action Cancer Application Known Example(s) ...

http://unithertechnologyconference.com/downloads09/SessionsDayOne/BURGESS_web.ppt

Date added: November 11, 2011 - Views: 28

ppt
Folie 1 - FLI - Leibniz

The Aptamer Database is a comprehensive, annotated repository for information about aptamers and in vitro selection. This resource is provided to collect, organize and distribute all the known information regarding aptamer selection.

http://www.fli-leibniz.de/www_bioc/3D/3D_LECTURE_2006_2.ppt

Date added: November 12, 2013 - Views: 1

ppt
PowerPoint Presentation

... Intracellular Peptide AS1411 (in dev.) Cell Surface, Intracellular Aptamer Her2, Erbitux Cell Surface Monoclonal Antibody Functionality Dispersion - Effective aqueous dispersion must be demonstrated. Preliminary results are encouraging. (internal research) ...

http://unithertechnologyconference.com/downloads/SESSION%205/Burgess_NEW.ppt

Date added: November 5, 2011 - Views: 25

ppt
No Slide Title

... 49-60 Aptamer remains receptive to FMN binding until it is disrupted by the formation of the antiterminator helix. = irreversible event of the riboswitch at low FMN concentrations longer transcripts have lower affinity aptamers of transcripts paused at PA and PB have affinities better ...

http://www.microbio.uab.edu/ptrm/neiderwies/niederweis.ppt

Date added: December 14, 2011 - Views: 14

ppt
Riboswitches - Weizmann Institute of Science

... Aptamer domain (responsible for binding of ligand) Expression plataform (responsible for impacting gene expression) Structure Mechanism Three known mechanisms: Formation of intrinsic terminator stem (inhibits transcription by inducing its termination) ...

http://www.weizmann.ac.il/plants/aharoni/FrontiersCourse/Sharon-Riboswitches3.ppt

Date added: May 11, 2013 - Views: 12

ppt
IBC Preclin Dev Forum Poster Feb 2005 - Bioautomation

Title: IBC Preclin Dev Forum Poster Feb 2005 Subject: poster ppt template Author: TGM Last modified by: Jeff Scheumack Created Date: 1/12/2000 10:46:20 PM

http://www.bioautomation.com/posters/Archemix%20Poster.ppt

Date added: May 6, 2013 - Views: 10

ppt
RNA secondary structure prediction and gene finding

The aptamer domain is a highly folded structure that selectively binds to the target metabolite. The expression platform converts metabolite binding events into changes in gene expression by harnessing changes in RNA folding that are brought about by ligand binding.

http://darwin.informatics.indiana.edu/col/courses/I519-12/Lecture/RNAfold.ppt

Date added: May 25, 2013 - Views: 28

ppt
PowerPoint Presentation

PEG PLGA Aptamer … + + + + Precipitate nanoparticles by dilution in water Mix in selected ratio Synthesis of 100 types of nanoparticles per minute Drug COOH NH PEG PLGA Aptamer … COOH NH PEG PLGA Aptamer … PEG PLGA Aptamer

http://www-mtl.mit.edu/mems/documents/Rohittalk.ppt

Date added: November 25, 2011 - Views: 39

ppt
PowerPoint Presentation

PPT提交时间:5月7日课后 * Aptamer-based Electrochemical Biosensors 基于核酸适体的电化学生物传感器 吴宗凯、刘文驰、杨晏泉、朱如意、王腾、张理升、孙斌 举例: Biosensors & Aptamer-based biosensors Typical aptamer-based electrochemical ...

http://www.chem.pku.edu.cn/wangy/inform-2.ppt

Date added: May 11, 2013 - Views: 8

ppt
Synthetic Biology: Design and characterization of ...

Discuss different stems and discuss the single and anti-sense stem first, then mention aptamer stem -----> aptamers Antiswitch RNA molecules are too small to and require an exact sequence, they cannot be made directly in the cells.

http://www.bio.davidson.edu/people/macampbell/students/NCAS_MPGmac.ppt

Date added: May 29, 2013 - Views: 6

ppt
슬라이드 1

How we fabricate nanodevices? Fabrication of nanotube devices by patterned growth technique. Polymer coating. Antibody or aptamer. functionalization

http://www.andrew.cmu.edu/org/nanotechnology-forum/Forum_5/Presentation/Poster%20Session/JO_Lee.pptx.ppt

Date added: January 29, 2013 - Views: 3

ppt
Diapositiva 1 - UB

Study of the interaction between the porphyrin TmPyP4 and the Thrombin Binding Aptamer (TBA) G-quadruplex Miquel del Toro1, Ramon Eritja2, Raimundo Gargallo1, Joaquim Jaumot1

http://www.ub.edu/gesq/dna/presentations/tba_tmpyp4.ppt

Date added: March 7, 2012 - Views: 14

ppt
Slide 1

A smaller capture agent (aptamer) increases the signal rate for a much smaller target (thrombin, 30 kD). 6.5 nm/hr Hybrid nanorod, nanosphere, and bipyramid substrate Increased Sensitivity: Nanoparticle Shape bipyramids nanospheres nanorods time (s) ...

http://mmptdpublic.jsc.nasa.gov/jscnano/CD/Session%202/Jason%20Hafner.ppt

Date added: January 3, 2013 - Views: 6

ppt
RFID Biosensors for the Detection of IEDs at 400 m Stand-off ...

Presently involved in aptamer, peptide, antibody and plasma-deposited hydrogels research. Currently developing an RFID/Biosensor. Technology Background (3) RFID/Biosensor An interrogation unit transmits an RF signal to an RFID/Biosensor.

http://zensensing.com/media/powerpoint/Hunt-and-Edmonson-DARPA-Presentation-Nov-16-2005.ppt

Date added: May 2, 2013 - Views: 3

ppt
PowerPoint Presentation

... Binds specific ligand Theophylline Theophylline aptamer Caffeine Synthesize de novo Terminator + YFP Add antiswitch On Off ‘Off’ antiswitch ‘On’ antiswitch Verify construction PCR products PCR products + Promoter ON OFF Caffeine Detector “Digital Decoder Device” Goal: ...

http://www.bio.davidson.edu/people/macampbell/students/Gemberling_defense.ppt

Date added: May 10, 2013 - Views: 3

ppt
No Slide Title

AUG RBS Excess cofactor binds aptamer. RBS and start codon are sequestered. Biosynthetic genes are not translated. Excess adenine switches ON synthesis of purine efflux protein. Without excess adenine, terminator blocks transcription.

http://www.ucd.ie/indmicro/patrick2/INDM2003Lec2(05).ppt

Date added: April 18, 2014 - Views: 2

ppt
Larry GCNN-LAN-082707 (final).ppt - - NCMI - Baylor College ...

... ErbB3 Targeted Aptamer-Nanoparticle Conjugate, Massachusetts General Hospital, Boston, Mass. Carolina Center of Cancer Nanotechnology Excellence, University of North Carolina, Chapel Hill, N.C. Nanosystems Biology Cancer Center, ...

http://ncmi.bcm.edu/ncmi/events/workshops/workshops_85/proceeding/Larry%20GCNN-LAN-082707%20%28final%29.ppt

Date added: May 5, 2013 - Views: 4

ppt
Gene Transfer and Immunogenicity Branch Site Visit May 31, 2012

... Cell-specific RNA aptamer (e.g. anti-IL-13Ra2 aptamer) Receptor (e.g. IL-13Ra2) Targeted lentiviral vector transduction: General outline * Targeted lentiviral vector transduction Future plans: ...

http://www.fda.gov/downloads/AdvisoryCommittees/CommitteesMeetingMaterials/BloodVaccinesandOtherBiologics/CellularTissueandGeneTherapiesAdvisoryCommittee/UCM341247.ppt

Date added: May 5, 2013 - Views: 7

ppt
Slide 1

A metabolite-binding ‘aptamer’ domain and … Riboswitch Functions U U U U U X 3 4 2 1 Direct (protein-free) binding of metabolite to RNA Metabolite-dependent regulation of genes These two activities are accomplished by two functionally separate domains on the RNA: ...

http://www.cs.duke.edu/~reif/temp/aptamers/medical%20applications%20aptamers/riboswitch%20regultation%20of%20gene%20expression/riboswitch_movie.ppt

Date added: February 9, 2012 - Views: 20